Algeria Angola Argentina Australia Bahrain Bangladesh Botswana Brazil Cameroon Canada Chile China Colombia Congo, Dem Rep of Cote d'Ivoire Egypt Ethiopia France Gabon Germany Ghana Hong Kong

India Indonesia Iraq Ireland Italy Japan Jordan Kenya Kuwait Lebanon Libya Macao Malaysia Mali Mauritius Mexico Morocco Mozambique Namibia Netherlands New Zealand Nigeria Oman Pakistan Palestine Philippines Poland Portugal Qatar Rwanda Saudi Arabia Senegal Singapore South Africa South Korea Spain Sri Lanka Sudan Sweden Switzerland Taiwan Tanzania Thailand Tunisia Turkey Uganda United Arab Emirates United Kingdom United States Vietnam Zambia Zimbabwe English 繁體中文

Fare Guide

Estimated lowest fares found within 7 days

The cheapest airline(s) flying from Santorini to Istanbul is Aegean Airlines.

Travel Period: May 2025 - April 2026

The cheapest month(s) to fly from Santorini to Istanbul is June.

May 2025
Jun 2025
Jul 2025
Aug 2025
Sep 2025
Oct 2025
Nov 2025
Dec 2025
Jan 2026
Feb 2026
Mar 2026
Apr 2026

The cheapest day(s) of the week to fly from Santorini to Istanbul is Wednesday.

Sun Sunday
Mon Monday
Tue Tuesday
Wed Wednesday
Thu Thursday
Fri Friday
Sat Saturday

Flight Schedules

Last Updated: Wed, 2 Apr, 2025

Time Earliest
- Earliest
- Latest
Depart Earliest
- Earliest
- Latest
Arrive
- Earliest
- Latest
Duration
- Shortest
- Longest
Stopover
All
Airline Filter by Airline
View All Airline
Availability
- M
- T
- W
- T
- F
- S
- S

06:00 JTR

12:05 IST

6Hrs, 05m 1 Stop (ATH)
JTRThira Airport 06:00 - IST 12:05 6h 05m 1 Stop (ATH) Athens
JTRThira Airport 06:00

ATHAthens Airport 10:25
ATHAthens Airport 07:00

ISTIstanbul Airport 12:05
6h 05m (3h 25m)
1 Stop ATH · Athens 3h 25m
Aegean Airlines (A3 351)Atr Turboprop

Turkish Airlines (TK 1844)Airbus A359
Aegean Airlines (A3 351)
- -
- -
- W
- -
- -
- -
- -

06:00 JTR

12:05 IST

6Hrs, 05m 1 Stop (ATH)
JTRThira Airport 06:00 - IST 12:05 6h 05m 1 Stop (ATH) Athens
JTRThira Airport 06:00

ATHAthens Airport 10:25
ATHAthens Airport 07:00

ISTIstanbul Airport 12:05
6h 05m (3h 25m)
1 Stop ATH · Athens 3h 25m
Aegean Airlines (A3 351)Atr Turboprop

Turkish Airlines (TK 1844)Boeing 777 300 Er
Aegean Airlines (A3 351)
- M
- T
- -
- T
- F
- S
- S

06:00 JTR

09:50 IST

3Hrs, 50m 1 Stop (ATH)
JTRThira Airport 06:00 - IST 09:50 3h 50m 1 Stop (ATH) Athens
JTRThira Airport 06:00

ATHAthens Airport 08:20
ATHAthens Airport 07:00

ISTIstanbul Airport 09:50
3h 50m (1h 20m)
1 Stop ATH · Athens 1h 20m
Aegean Airlines (A3 351)Atr Turboprop

Aegean Airlines (A3 990)Airbus
Aegean Airlines (A3 351)
- M
- T
- W
- T
- F
- S
- S

08:25 JTR

15:00 IST

6Hrs, 35m 1 Stop (ATH)
JTRThira Airport 08:25 - IST 15:00 6h 35m 1 Stop (ATH) Athens
JTRThira Airport 08:25

ATHAthens Airport 13:25
ATHAthens Airport 09:15

ISTIstanbul Airport 15:00
6h 35m (4h 10m)
1 Stop ATH · Athens 4h 10m
Aegean Airlines (A3 353)Airbus

Aegean Airlines (A3 992)Airbus
Aegean Airlines (A3 353)
- M
- T
- W
- T
- F
- S
- S

11:35 JTR

17:20 IST

5Hrs, 45m 1 Stop (ATH)
JTRThira Airport 11:35 - IST 17:20 5h 45m 1 Stop (ATH) Athens
JTRThira Airport 11:35

ATHAthens Airport 15:40
ATHAthens Airport 12:25

ISTIstanbul Airport 17:20
5h 45m (3h 15m)
1 Stop ATH · Athens 3h 15m
Aegean Airlines (A3 355)Airbus

Turkish Airlines (TK 1850)Airbus
Aegean Airlines (A3 355)
- M
- T
- W
- T
- -
- -
- -

11:35 JTR

17:20 IST

5Hrs, 45m 1 Stop (ATH)
JTRThira Airport 11:35 - IST 17:20 5h 45m 1 Stop (ATH) Athens
JTRThira Airport 11:35

ATHAthens Airport 15:40
ATHAthens Airport 12:25

ISTIstanbul Airport 17:20
5h 45m (3h 15m)
1 Stop ATH · Athens 3h 15m
Aegean Airlines (A3 355)Airbus

Turkish Airlines (TK 1850)Airbus Industrie A321 Sharklets
Aegean Airlines (A3 355)
- -
- -
- -
- -
- F
- S
- S

12:30 JTR

17:20 IST

4Hrs, 50m 1 Stop (ATH)
JTRThira Airport 12:30 - IST 17:20 4h 50m 1 Stop (ATH) Athens
JTRThira Airport 12:30

ATHAthens Airport 15:40
ATHAthens Airport 13:20

ISTIstanbul Airport 17:20
4h 50m (2h 20m)
1 Stop ATH · Athens 2h 20m
Aegean Airlines (A3 357)Airbus

Turkish Airlines (TK 1850)Airbus
Aegean Airlines (A3 357)
- M
- -
- -
- T
- -
- -
- -

12:30 JTR

17:20 IST

4Hrs, 50m 1 Stop (ATH)
JTRThira Airport 12:30 - IST 17:20 4h 50m 1 Stop (ATH) Athens
JTRThira Airport 12:30

ATHAthens Airport 15:40
ATHAthens Airport 13:20

ISTIstanbul Airport 17:20
4h 50m (2h 20m)
1 Stop ATH · Athens 2h 20m
Aegean Airlines (A3 357)Airbus

Turkish Airlines (TK 1850)Airbus Industrie A321 Sharklets
Aegean Airlines (A3 357)
- -
- -
- -
- -
- F
- -
- S

12:30 JTR

17:20 IST

4Hrs, 50m 1 Stop (ATH)
JTRThira Airport 12:30 - IST 17:20 4h 50m 1 Stop (ATH) Athens
JTRThira Airport 12:30

ATHAthens Airport 15:40
ATHAthens Airport 13:30

ISTIstanbul Airport 17:20
4h 50m (2h 10m)
1 Stop ATH · Athens 2h 10m
Aegean Airlines (A3 357)Atr Turboprop

Turkish Airlines (TK 1850)Airbus
Aegean Airlines (A3 357)
- -
- T
- W
- -
- -
- -
- -

14:55 JTR

20:45 IST

5Hrs, 50m 1 Stop (ATH)
JTRThira Airport 14:55 - IST 20:45 5h 50m 1 Stop (ATH) Athens
JTRThira Airport 14:55

ATHAthens Airport 19:15
ATHAthens Airport 15:50

ISTIstanbul Airport 20:45
5h 50m (3h 25m)
1 Stop ATH · Athens 3h 25m
Sky Express (GQ 349)Atr

Sky Express (GQ 670)Airbus A320 Neo
Sky Express (GQ 349)
- -
- -
- -
- -
- -
- -
- S

15:05 JTR

20:00 IST

4Hrs, 55m 1 Stop (ATH)
JTRThira Airport 15:05 - IST 20:00 4h 55m 1 Stop (ATH) Athens
JTRThira Airport 15:05

ATHAthens Airport 18:30
ATHAthens Airport 15:55

ISTIstanbul Airport 20:00
4h 55m (2h 35m)
1 Stop ATH · Athens 2h 35m
Aegean Airlines (A3 367)Airbus

Aegean Airlines (A3 994)Airbus
Aegean Airlines (A3 367)
- M
- T
- W
- T
- F
- S
- S

15:25 JTR

20:45 IST

5Hrs, 20m 1 Stop (ATH)
JTRThira Airport 15:25 - IST 20:45 5h 20m 1 Stop (ATH) Athens
JTRThira Airport 15:25

ATHAthens Airport 19:15
ATHAthens Airport 16:20

ISTIstanbul Airport 20:45
5h 20m (2h 55m)
1 Stop ATH · Athens 2h 55m
Sky Express (GQ 351)Atr

Sky Express (GQ 670)Airbus A320 Neo
Sky Express (GQ 351)
- -
- -
- -
- -
- -
- -
- S

18:40 JTR

23:40 IST

5Hrs, 00m 1 Stop (ATH)
JTRThira Airport 18:40 - IST 23:40 5h 1 Stop (ATH) Athens
JTRThira Airport 18:40

ATHAthens Airport 22:00
ATHAthens Airport 19:40

ISTIstanbul Airport 23:40
5h (2h 20m)
1 Stop ATH · Athens 2h 20m
Aegean Airlines (A3 359)Atr Turboprop

Turkish Airlines (TK 1846)Boeing 777 300 Er
Aegean Airlines (A3 359)
- M
- -
- -
- -
- -
- -
- -

18:40 JTR

23:40 IST

5Hrs, 00m 1 Stop (ATH)
JTRThira Airport 18:40 - IST 23:40 5h 1 Stop (ATH) Athens
JTRThira Airport 18:40

ATHAthens Airport 22:00
ATHAthens Airport 19:30

ISTIstanbul Airport 23:40
5h (2h 30m)
1 Stop ATH · Athens 2h 30m
Aegean Airlines (A3 359)Airbus

Turkish Airlines (TK 1846)Boeing 777 300 Er
Aegean Airlines (A3 359)
- -
- T
- W
- T
- -
- S
- S

22:00 JTR

02:20 IST

4Hrs, 20m 1 Stop (ATH)
JTRThira Airport 22:00 - IST 02:20 4h 20m 1 Stop (ATH) Athens
JTRThira Airport 22:00

ATHAthens Airport 00:50
ATHAthens Airport 23:00

ISTIstanbul Airport 02:20
4h 20m (1h 50m)
1 Stop ATH · Athens 1h 50m
Aegean Airlines (A3 361)Atr Turboprop

Aegean Airlines (A3 998)Airbus
Aegean Airlines (A3 361)
- -
- T
- W
- T
- F
- S
- S

Sorry, there are no schedules matching your filters. Try removing one. reset

What’s the most popular airline flying from Santorini to Istanbul?

The most popular airline flying from Santorini to Istanbul is Aegean Airlines. Find the latest flight deals on Wego.

How far is Istanbul from Santorini?

The flight distance between Santorini and Istanbul is 596km. Check all available flights on Wego.

When is the earliest and latest flight of the day?

The earliest flight of the day departs at 06:00. The last flight of the day departs at 06:00. See the full list of flight times on Wego.

Popular Airlines Flying From Santorini to Istanbul

Aegean Airlines ‏()

Ryanair ‏()

Popular Destinations From Istanbul

Popular Destinations From Santorini

Popular Hotels in Istanbul

Hotels In Popular Destinations

Wego searches for the best deals on these sites & many more